Principal Investigator 

Bend, OR 

Do you: 

  • Like finding new and better ways to do things? 
  • Want to help develop medicines to make patients’ lives better? 
  • Desire to learn and grow? 
  • Nerd out on science & technology? 
  • Value people and working in a collaborative team? 
  • Desire to be audacious and entrepreneurial? 
  • Value safety and leading by example? 
  • Care about doing the right thing? 

At Bend Bioscience, we are looking for colleagues with: SCIENTIFIC CURIOSITY, HONESTY, HUMOR, CONFIDENCE, HUMILITY, TRUSTWORTHINESS, RESPECT FOR CO-WORKERS, and the DESIRE TO MAKE A DIFFERENCE AND HELP PATIENTS. 

 

Job Description:  

Bend Bioscience is focused on the development and clinical production of non-sterile drug products and intermediates for the pharmaceutical industry. In this role, you will provide oversight for all technical aspects and stages of the program lifecycle. Success will be achieved by designing and optimizing experiments and reviewing, interpreting, and responding to data with the goal of progressing robust formulations and processes. The Principal Investigator will oversee formulation, process development, and manufacturing for spray dried intermediates and finished drug products. 

 

The Principal Investigator works collaboratively with other departments and client teams and will be responsible to progress compounds with multi-disciplinary teams by: 

  • Leading internal project teams and consulting site subject matter experts (SMEs) to solve unique and complex problems that have a broad impact on the business and enable progression of challenging compounds.  
  • Managing multi-disciplinary project teams of scientists for technical capability, program progression and career growth.  
  • Working with clients and internal SMEs to define problem statements, technology selection, and outline technical program strategies based on target product profile.  
  • Leading programs to ensure quality of technical approach, progress reports, and successful client relationships.  
  • Understanding, reviewing, and optimizing workplans to effectively challenge formulation attributes critical to successful formulation strategies. 
  • Being and subject matter expert in at least one focus area of the program lifecycle and staying aware and current with pharmaceutical industry formulation and process advancements.  
  • Presenting technical results and recommendations to the client.  Serving as the primary technical point of contact for client programs (internally and externally). 
  • Utilizing risk assessments to effectively communicate and plan for program considerations associated with formulations and processes. 
  • Supporting GMP manufacturing by participating in activities, including, development study design and execution, training, clinical tech transfer, investigation support, equipment design and qualification, and change control. 
  • Identifying and proposing new technical opportunities while working on client programs. 

 

Experience and Educational Requirements: 

  • PhD, MS, or BS in chemistry, chemical engineering, or related field with minimum 5 years of experience in pharmaceutical industry with a focus on chemistry, manufacturing, and controls.  
  • Experience with oral solid dosage form manufacturing equipment and processing parameters including scale-up and support for GMP manufacturing. 
  • Experience and understanding of the fundamentals of processes and formulation development for spray dried dispersions.