Oral Dosage Form Design
Elegant solutions for optimal oral dosage formulation and processing
Your patients are unique and so is your molecule. That’s why we apply our best science and engineering to create safe, pure, and effective drug products that are stable, convenient, cost effective, and performant.
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Our Approach
A successful drug product needs four things:
- A formulation that is stable, convenient for the patient and healthcare provider, and that delivers the correct dose at the right time and place.
- A process that is robust and cost-effective.
- Analytical methods that are specific, accurate, precise, reproducible, and robust.
- Proper understanding and documentation of the development to support future transfers, material changes.
All of these things interact in sometimes complex ways. That’s why we take a holistic design approach to deeply understand the characteristics of your molecule and consider how they interact with your therapeutic indication, patient population, healthcare provider needs, and manufacturing process conditions.
We use this analysis to recommend a formulation and process design approach that considers all the factors to develop formulations that optimize bioavailability, stability, and patient acceptability and satisfy your target product profile as quickly and flexibly as possible.
Formulation Design Services
- Molecular Properties
- Solubility, permeability, stability, and reactivity profiles to select appropriate formulation strategies
- Clinical Requirements
- Dose range, patient population needs, administration setting (hospital vs. home), desired dosing frequency, and pharmacokinetic targets
- Risk Management
- Addressing potential risks of overdose or underdose through precise formulation control and appropriate release mechanisms
- Manufacturing Factors
- Process robustness, scalability, cost of goods, and packaging compatibility to ensure commercial viability
Our Expertise
- We don’t just design copycat formulations. We design viable commercial products.
- We balance scientific innovation with practical constraints, considering administrative and logistical challenges, cost implications, formulation and process risk from the earliest stages. This forward-thinking approach manages future risk and accelerates your path to market.
- We do what’s right for you and your patients. If our design assessment suggests you should take an approach that is not in our capabilities, we’ll tell you honestly.
Whether we’re developing immediate-release tablets or complex bioavailability-enhanced or modified-release systems, we work hard to design formulations, processes, and methods that transform challenging molecules into remarkable therapies.
Design • Develop • Manufacture
Let's build something remarkable